EURURO Vol. 72 No. 5

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Table 1 – Baseline study characteristics for the 20 comparative studies with 4505 patientsFirst author (year)
Study
start–end
Follow-up
(median; mo)
Uropathologist Patients
included
Patientsexcluded
Age
(mean)
Males/females
T category
Ta/T1
CIS Intravesical
chemotherapy
BCG G1 G2 G3 PUNLMP LG HG
Mangrud (2014)
[16]
2002–2006
75.0
No
193
56
148/45 Ta and T1 22
193
44 98 51
0 119 74
Gontero (2014)
[18]
1992–2006
71.6
Yes
131
60
66.3 112/19 Only Ta
5
65
65 0 105 26
0
0 131
Nishiyama (2013)
[19]
1995–2010
No
153
68.5 122/31 Ta and T1
49
24 2 89 62
0
37 116
Chen (2012)
1999–2009
47.0
Yes
348
44
287/61 Ta and T1 21
-
125 176 47
40 223 85
Pellucchi (2011)
2004–2008
25.0
Yes
270
162
220/50 Only Ta
270
87 183 0
0 270 0
Pellucchi (2015)
2004–2011
19. 0
Yes
266
412
67.6 237/29 Only T1
71
266 0 124 142
0
0 266
Otto (2011)
1989–2006
49.0
Yes
310
39
71.7 239/71 Only T1
252 0 112 198
0
13 297
Ishida (2010)
–
67.0
Yes
132
0
69
107/25 Only Ta
21
51 68 13
0
77 55
Van Rhijn (2010)
[25]
1983–2006
68.0
Yes
164
-
68.6 135/29 Ta and T1 55
26
164 0 74 90
0
37 127
Burger (2008)
1985–2002
48
Yes
109
60
97/12
Only Ta
6
58 46 5
6
77 26
Burger (2008)
Yes
221
0
171/50 Ta and T1
86 110 25
49 119 50
Schned (2007)
[28]
1994–2000
No
504
353
61.5 376/128 Only Ta
295 154 55 179 214 73
Kamel (2006)
1991–2003
48
No
105
–
85/20
Only T1
15
25
24 0 61 44
0
0 105
Yin (2004)
[30]
1995–2000
No
84
0
69.4 –
Only Ta
32 46 3
12
53 19
Oosterhuis (2002)
[31]
1979–2000
63
No
320
39
66.6 295/64 Only Ta
28
8 31 286 1 116 141 45
Samaratunga (2002)
[32]
–
50
–
134
–
65.7 95/39
Only Ta
16 42 79 6
29
73 29
Holma¨ng (2001)
[17]
1987–1989
No
363
317
–
Only Ta
3
0 255 95 13
95 160 108
van Rhijn (2010)
1983–2001
Yes
173
–
64.9 129/44 Ta and T1 15
79
75 25 97 51
18
69 86
May (2010)
[33]
1997–2004
Yes
200
–
68.6 149/51 Only Ta
0
82 109 9
1 149 50
van Rhijn (2015)
1986–2006
Yes
325
0
66.4 254/71 Ta and T1 62
98
225 88 149 88
79 101 145
CIS = carcinoma in situ; G1 = grade 1; G2 = grade 2; G3 = grade 3; HG = high grade; LG = low grade; PUNLMP = papillary urothelial neoplasm with low malignant potential.a
Studies included in the reproducibility part.
E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 8 0 1 – 8 1 3 805