808 860
Table 3 – Distribution of the percentage of patients with tumour recurrence
Type of analysis
1973
grade—studies
included
1973
grade—
number
of patients
1973
grade—
percent
of G1
patients
with
recurrence
1973
grade—
percent
of G2
patients
with
recurrence
1973
grade—
percent
of G3
patients
with
recurrence
Pearson
x
2
test
p
value
2004/2016
grade—studies
included
2004/2016
grade—
number
of patients
2004/2016
grade—
percent of
PUNLMP
patients
with
recurrence
2004/2016
grade—
percent
of LG
patients
with
recurrence
2004/2016
grade–
percent
of HG
patients
with
recurrence
Pearson
x
2
test
p
value
Studies in which
both 1973 and
1998/2004 can
be compared
Mangrud (2014)
[16]
,Chen (2012)
[20] ,Burger (2008)
[26]
,Yin (2004)
[30] ,May (2010)
[33]931
32.6
42.3
62.6
0.000
Mangrud (2014)
[16]
,Chen (2012)
[20] ,Burger (2008)
[26]
,Yin (2004)
[30]
,May (2010)
[33]934
20.3
38.0
54.7
0.000
All studies with
recurrence data
Mangrud (2014)
[16]
,Chen (2012)
[20] ,Pellucchi (2015)
[22]
,Burger (2008)
[26]
,Yin (2004)
[30] ,May (2010)
[33]1197
32.6
43.9
65.4
0.000
Mangrud (2014)
[16]
,Chen (2012)
[20] ,Pellucchi (2015)
[22]
,Burger (2008)
[26]
,Yin (2004)
[30]
,Oosterhuis (2002)
[31]
,Holma¨ng (2001)
[17]
,May (2010)
[33]1865
27.8
42.6
58.4
0.000
Ta patients only
Burger (2008)
[26]
,Yin (2004)
[30] ,May (2010)
[33]390
39.0
40.8
70.6
0.040
Burger (2008)
[26]
,Yin (2004)
[30]
,Oosterhuis (2002)
[31]
,Holma¨ng (2001)
[17]
,May (2010)
[33]988
28.3
52.0
60.5
0.000
T1 patients only
Pellucchi (2015)
[22]
266
–
50.0
67.6
0.004
Pellucchi (2015)
[22]
266
–
–
59.4
–
G2 vs G3 in T1
HG tumours
Pellucchi (2015)
[22]
266
–
50.0
67.6
0.004
Pellucchi (2015)
[22]
266
–
–
59.4
–
G1 = grade 1; G2 = grade 2; G3 = grade 3; HG = high grade; LG = low grade; PUNLMP = papillary urothelial neoplasm with low malignant potential.
E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 8 0 1 – 8 1 3
808