

Table 2 – Summary of the included studies
Study
Research setting
Qualitative methods
Bill-Axelson et al (2009)
[23]Main study comparing radical prostatectomy with active monitoring
for prostate cancer in Sweden
Interviews with patients (
n
= 9) and clinicians (
n
= 5)
Blazeby et al (2009)
[24]Feasibility study comparing chemoradiation versus chemotherapy
and surgery for oesophageal cancer in the UK
Interviews with patients (
n
= 14)
RCT consultations recorded (
n
= 26)
Donovan et al (2009)
[25]Feasibility/main study comparing prostatectomy, radiotherapy, and
active monitoring for prostate cancer in UK
Interviews with recruiters and patients
RCT consultations recorded
Donovan et al (2014)
[27]Six UK RCTs in a range of clinical contexts, with different types of RCT
interventions, with a range of primary recruiters, and at different
stages of the implementation of the RCT
Interviews with clinicians and nurses (
n
= 72)
Donovan et al (2014)
[28]Six UK RCTs in a range of clinical contexts, with different types of RCT
interventions, with a range of primary recruiters, and at different
stages of the implementation of the RCT
Interviews with clinicians (
n
= 32)
French et al (2016)
[29]Specialist nurses from a variety of research studies (including RCTs) in
general adult acute care or community settings in the UK
Interviews with specialist nurses (
n
= 12)
Hales et al (2001)
[30]RCT for an HIV drug in Australia
Interviews with clinicians (
n
= 10)
Griffin et al (2016)
[31]Feasibility study comparing surgery and nonoperative care for hip
impingement in the UK
Interviews with TMG (
n
= 10) and clinicians (
n
= 21)
RCT consultations recorded (
n
= 87)
Hamilton et al (2013)
[32]Feasibility study comparing surgery or radiotherapy for laryngeal
cancer in the UK
Interviews with clinicians and research nurses
RCT consultations recorded
Horwood et al (2016)
[33]Main study comparing intraoperative local anaesthetic wound
infiltration or usual care for joint pain in the UK
Interviews with patients (
n
= 24) and clinicians/nurses
(
n
= 15)
Lamb et al (2016)
[34]Community nurses involved in wound care trials in the UK
Interviews with research nurses (
n
= 8)
Langley et al (2000)
[35]Clinicians recruiting to cancer trials in the UK
Interviews with clinicians (
n
= 20)
Lawton et al (2015)
[36]Type 1 diabetes main RCT comparing multiple daily injections or
pump therapy in the UK
Interviews with clinicians and nurses (
n
= 18)
Lawton et al (2016)
[37]Peripartum pilot RCT comparing drug with placebo in the UK
Interviews with clinicians/nurses (
n
= 27) and patients
(
n
= 22)
Mann et al (2014)
[38]Pilot study comparing intraoperative local anaesthetic wound
infiltration or usual care for joint pain in the UK
RCT consultations recorded (
n
= 53)
Mason et al (2007)
[39]Main study comparing types of antidepressants for depression RCT in
the UK
Interviews with recruiting GPs (
n
= 41)
Mills et al (2014)
[40]Feasibility/main study comparing prostatectomy, radiotherapy, and
active monitoring for prostate cancer in the UK and two anonymised
RCTs
RCT consultations recorded (
n
= 103)
Mills et al (2011)
[41]Feasibility/main study comparing prostatectomy, radiotherapy, and
active monitoring for prostate cancer in the UK
RCT consultations recorded (
n
= 93)
McIntosh et al (2005)
[42]Smoking cessation trial in the USA
Focus groups with clinicians (
n
= 30)
Newington et al (2014)
[43]Clinicians and nurses involved in research (including RCTs) in the UK Interviews with clinicians and nurses (
n
= 11)
Paramasivan et al (2011)
[44]Feasibility study comparing surgery with radiotherapy for bladder
cancer in the UK
Interviews with clinicians/nurses (
n
= 9) and TMG (
n
= 2)
RCT consultations recorded (
n
= 4)
Paramasivan et al (2015)
[45]Two anonymised UK RCTs differed in clinical contexts and complexity
of the recruitment process
Interviews with clinicians/nurses (
n
= 20) and patients
(
n
= 23)
RCT consultations recorded (n = 35)
Patterson et al (2010)
[46]Main RCT comparing art therapy with usual care for schizophrenia in
the UK
Interviews and focus groups with clinicians (
n
= 17)
Potter et al (2009)
[47]Main RCT comparing telephone support with usual care for type
2 diabetes in the UK
Interviews with nurses (
n
= 10)
Potter et al (2014)
[48]Hypothetical feasibility RCT in breast reconstruction after
mastectomy for breast cancer in the UK
Interviews with clinicians (
n
= 31)
Rooshenas et al (2016)
[49]Six UK RCTs in a range of clinical contexts, with different types of RCT
interventions, with a range of primary recruiters, and at different
stages of the implementation of the RCT
Interviews with clinicians (
n
= 23)
RCT consultations recorded (
n
= 105)
de Salis et al (2008)
[50]Five UK RCTs in a range of clinical contexts, with different types of
RCT interventions, with a range of primary recruiters, and at different
stages of the implementation of the RCT
Interviews with clinicians and nurses
RCT consultations recorded
Spilsbury et al (2008)
[51]Main RCT comparing alternating pressure mattress overlays and
replacements
Focus group with nurses (
n
= 9)
Stein et al (2016)
[52]Feasibility RCT comparing test direct chemotherapy versus usual care
in the UK
Interviews with clinicians and nurses (
n
= 14)
RCT consultations recorded (
n
= 36)
Stuart et al (2015)
[53]Main RCT comparing home-based support with usual care for
pregnant women in the UK
Interviews with community midwives (
n
= 13)
Strong et al (2016)
[54]Feasibility study comparing chemoradiation versus chemotherapy
and surgery for oesophageal cancer in the UK
Interviews with clinicians (
n
= 21)
Tomlin et al (2014)
[55]Five UK RCTs in a range of clinical contexts, with different types of
RCT interventions, with a range of primary recruiters, and at different
stages of the implementation of the RCT
Interviews and focus groups with nurses (
n
= 43)
RCT consultations recorded (
n
= 23)
Wade et al (2009)
[13]Feasibility/main study comparing prostatectomy, radiotherapy, and
active monitoring for prostate cancer in the UK
RCT consultations recorded (
n
= 23)
Zeibland et al (2007)
[56]Main study comparing spinal rehabilitation with surgery for
treatment of chronic back pain in the UK
Interviews with clinicians (
n
= 11)
GP = general practitioner; RCT = randomised controlled trial; TMG = trial management group.
E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 7 8 9 – 7 9 8
792